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Structure of PDB 1ga2 Chain A

Receptor sequence
>1ga2A (length=611) Species: 1521 (Ruminiclostridium cellulolyticum) [Search protein sequence]
YNYGEALQKSIMFYEFQRSGDLPADKRDNWRDDSGMKDGSDVGVDLTGGW
YDAGDHVKFNLPMSYTSAMLAWSLYEDKDAYDKSGQTKYIMDGIKWANDY
FIKCNPTPGVYYYQVGDGGKDHSWWGPAEVMQMERPSFKVDASKPGSAVC
ASTAASLASAAVVFKSSDPTYAEKCISHAKNLFDMADKAKSDAGYTAASG
YYSSSSFYDDLSWAAVWLYLATNDSTYLDKAESYVPNWGKEQQTDIIAYK
WGQCWDDVHYGAELLLAKLTNKQLYKDSIEMNLDFWTTGVNGTRVSYTPK
GLAWLFQWGSLRHATTQAFLAGVYAEWEGCTPSKVSVYKDFLKSQIDYAL
GSTGRSFVVGYGVNPPQHPHHRTAHGSWTDQMTSPTYHRHTIYGALVGGP
DNADGYTDEINNYVNNEIACDYNAGFTGALAKMYKHSGGDPIPNFKAIEK
ITNDEVIIKAGLNSTGPNYTEIKAVVYNQTGWPARVTDKISFKYFMDLSE
IVAAGIDPLSLVTSSNYSEGKNTKVSGVLPWDVSNNVYYVNVDLTGENIY
PGGQSACRREVQFRIAAPQGTTYWNPKNDFSYDGLPTTSTVNTVTNIPVY
DNGVKVFGNEP
3D structure
PDB1ga2 X-Ray Crystal Structure of the Multidomain Endoglucanase Cel9G from Clostridium cellulolyticum Complexed with Natural and Synthetic Cello-Oligosaccharides
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D55 D58 Y205 E420
Catalytic site (residue number reindexed from 1) D52 D55 Y202 E417
Enzyme Commision number 3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A W258 W311 R315 W255 W308 R312
BS02 BGC A C257 D259 C254 D256
BS03 BGC A W254 D259 D260 W251 D256 D257
BS04 BGC A H373 R375 Y416 E420 H370 R372 Y413 E417
BS05 CA A S209 D212 D213 D259 S206 D209 D210 D256
BS06 CA A D500 E503 N578 N581 D582 D497 E500 N575 N578 D579
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0030246 carbohydrate binding
GO:0030248 cellulose binding
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1ga2, PDBe:1ga2, PDBj:1ga2
PDBsum1ga2
PubMed12837787
UniProtP37700|GUNG_RUMCH Endoglucanase G (Gene Name=celCCG)

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