BioLiP

Structure of PDB 1be0 Chain A

Receptor sequence

>1be0A (length=310) Species: 280 (Xanthobacter autotrophicus) [Search protein sequence]

MVNAIRTPDQRFSNLDQYPFSPNYLDDLPGYPGLRAHYLDEGNSDAEDVF
LCLHGEPTWSYLYRKMIPVFAESGARVIAPDFFGFGKSDKPVDEEDYTFE
FHRNFLLALIERLDLRNITLVVQDWGGFLGLTLPMADPSRFKRLIIMNAC
LMTDPVTQPAFSAFVTQPADGFTAWKYDLVTPSDLRLDQFMKRWAPTLTE
AEASAYAAPFPDTSYQAGVRKFPKMVAQRDQACIDISTEAISFWQNDWNG
QTFMAIGMKDKLLGPDVMYPMKALINGCPEPLEIADAGHFVQEFGEQVAR
EALKHFAETE

3D structure

PDB

1be0 Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site.

Chain

Resolution

1.96 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	E56 D124 W125 N148 W175 D260 H289
Catalytic site (residue number reindexed from 1)	E56 D124 W125 N148 W175 D260 H289
Enzyme Commision number	3.8.1.5: haloalkane dehalogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ACY	A	D124 W125 F172 W175	D124 W125 F172 W175

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0016787	hydrolase activity
GO:0018786	haloalkane dehalogenase activity

	Biological Process
GO:0009636	response to toxic substance
GO:0019260	1,2-dichloroethane catabolic process

View graph for
Molecular Function

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Biological Process

PDB	RCSB:1be0, PDBe:1be0, PDBj:1be0
PDBsum	1be0
PubMed	9790663
UniProt	P22643\|DHLA_XANAU Haloalkane dehalogenase (Gene Name=dhlA)