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BioLiP

Structure of PDB 1a0d Chain A

Receptor sequence
>1a0dA (length=437) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
PYFDNISTIAYEGPASKNPLAFKFYNPEEKVGDKTMEEHLRFSVAYWHTF
TGDGSDPFGAGNMIRPWNKYSGMDLAKARVEAAFEFFEKLNIPFFCFHDV
DIAPEGETLKETYKNLDIIVDMIEEYMKTSKTKLLWNTANLFTHPRFVHG
AATSCNADVFAYAAAKVKKGLEIAKRLGAENYVFWGGREGYETLLNTDMK
LELDNLARFLHMAVDYAKEIGFDGQFLIEPKPKEPTKHQYDFDVATALAF
LQTYGLKDYFKFNIEANHATLAGHTFEHELRVARIHGMLGSVDANQGDML
LGWDTDEFPTDLYSTTLAMYEILKNGGLGRGGLNFDAKVRRGSFEPEDLF
YAHIAGMDSFAVGLKVAHRLIEDRVFDEFIEERYKSYTEGIGREIVEGTA
DFHKLEAHALQLGEIQNQSGRQERLKTLLNQYLLEVC
3D structure
PDB1a0d High Level Expression of a Thermostable Bacillus Xylose (Glucose) Isomerase in Escherichia Coli
ChainA
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H98 D101 W136 E229 K231 E265 H268 D293 D304 D306 D336
Catalytic site (residue number reindexed from 1) H98 D101 W136 E229 K231 E265 H268 D293 D304 D306 D336
Enzyme Commision number 5.3.1.5: xylose isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E229 E265 D293 D336 E229 E265 D293 D336
BS02 MN A E265 H268 D304 D306 E265 H268 D304 D306
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0009045 xylose isomerase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0042732 D-xylose metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1a0d, PDBe:1a0d, PDBj:1a0d
PDBsum1a0d
PubMed
UniProtP54273|XYLA_GEOSE Xylose isomerase (Gene Name=xylA)

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