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Structure of PDB 5kjh Chain B Binding Site BS09

Receptor Information
>5kjh Chain B (length=807) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WTVDKIASALSVLAEEVPQNHSRLVNFLLEETEKRAPQPRHLSKTDPFAH
MKSKAIDANRPRPEGVPTMDVKFKQHSGEYGKSRNSGRRFQYPVVCIKPD
REPVPPYRFHHAEIRKNILALNSQLNFVPHLRDVDPNSAEEQKYSAWLMD
LENLDSKSGFPRSQKIAKRAQAEYAATLAPYLEPWLRKLNIECTKSNLIR
FMASQPETPQQKSNLLDTYSDDAVRNASMFTEAWDRVFNDQRRVALRDIL
MLDKNVEPIFEALMQKVIDALGSYTTLGCLICFSHDCEHGEIERDNQKRC
FSLEEIGGLMPSLRRKWAAQIEQPPCRNECYIHGTPPWSENEVGTLEWMF
ATIGYSLRPECFVGAILRPCWDVHRKLQELDLRLPIPKQKSLPWYDRRKK
QLMSDWADATITHEHAVRELFAPCHHDGPCTAANGCPCASAGTHPVLCER
FCLCTAEECPLKFTGCACHSSGKTCLQRQGRPCICVQLNRECDPTLCKGC
GARERADPENAYDEVLHSTGCQNVALQRGAAKAVVLGKSQLEACGYGLFA
AEDIEEGEFVIEYTGELISHDEGVRREHRRGDVFDKVSYLFTLLEQEGIW
VDAAIYGNLSRYINHATDGNIMPKIMYVNHEWRIKFTAIKDIKAGEELFF
NYGDNFPNLTKKLEVMLPGRGVPPLLVPKTTQPLFDPLSKVQLLPGQPLP
QHPIDDSWLLLKHRDNLQDFIDLRPEEKEFLQEWDAFILRRHISSEQYLP
RYFLRFVREKADWLVSKRSRGEEFSKLVATLLARRVLPERVVIEATQVLN
DARGRLR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5kjh Chain B Residue 8008 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kjh Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Resolution2.27 Å
Binding residue
(original residue number in PDB)		C570 C574 C615 C625
Binding residue
(residue number reindexed from 1)		C326 C330 C361 C370
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Y826 Y918
Catalytic site (residue number reindexed from 1) Y563 Y652
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling

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Molecular Function
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Biological Process
External links

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