Structure of PDB 7pjy Chain x Binding Site BS04

Receptor Information

>7pjy Chain x (length=697) Species: 83333 (Escherichia coli K-12)

ARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVMDWMEQEQ
ERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLD
GAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQ
IKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDI
PADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVL
NNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPA
ERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAAR
ERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILE
RMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTI
IAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAK
QSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGI
QEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKK
AKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAE
VPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK

Ligand information

>7pjy Chain z (length=10)

uauguuuguu

..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7pjy Structural mechanism of GTPase-powered ribosome-tRNA movement.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): G510 R511
• Binding residue (residue number reindexed from 1): G504 R505

Enzymatic activity

• Enzyme Commision number: 3.6.5.-

Gene Ontology

Molecular Function

• GO:0003746 translation elongation factor activity
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0016787 hydrolase activity
• GO:0097216 guanosine tetraphosphate binding

Biological Process

• GO:0006412 translation
• GO:0006414 translational elongation
• GO:0032790 ribosome disassembly

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:7pjy, PDBe:7pjy, PDBj:7pjy
• PDBsum: 7pjy
• PubMed: 34635670
• UniProt: P0A6M8|EFG_ECOLI Elongation factor G (Gene Name=fusA)