Structure of PDB 4zma Chain L Binding Site BS04

Receptor Information
>4zma Chain L (length=141) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQC
ASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQ
YCSDHKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4zma Chain L Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4zma Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		A1 N2 E6 E7 E16 E26
Binding residue
(residue number reindexed from 1)		A1 N2 E6 E7 E16 E26
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:4zma, PDBe:4zma, PDBj:4zma
PDBsum4zma
PubMed26694616
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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