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BioLiP

Structure of PDB 2hib Chain X Binding Site BS03

Receptor Information
>2hib Chain X (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTE
FEKFVNSTGYLTEAEKFGDSFVFEGMLAAAPWWLPVKGANWRHPEGPDST
ILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWG
NKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGN
AWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMSHRSYCYRYRCA
ARSQNTPDSSASNLGFRCAADRLP
Ligand information
Ligand IDIOD
InChIInChI=1S/HI/h1H/p-1
InChIKeyXMBWDFGMSWQBCA-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[I-]
FormulaI
NameIODIDE ION
ChEMBL
DrugBankDB12754
ZINC
PDB chain2hib Chain X Residue 1006 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hib Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		W299 S336 C341
Binding residue
(residue number reindexed from 1)		W202 S239 C244
Annotation score1
Enzymatic activity
Enzyme Commision number 1.8.3.7: formylglycine-generating enzyme.
External links
PDB RCSB:2hib, PDBe:2hib, PDBj:2hib
PDBsum2hib
PubMed17452787
UniProtQ8NBK3|SUMF1_HUMAN Formylglycine-generating enzyme (Gene Name=SUMF1)

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