Structure of PDB 9fmd Chain P Binding Site BS03
Receptor Information
>9fmd Chain P (length=106) Species:
9606
(Homo sapiens) [
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TTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAP
EEVRNRDFRRELEERERAAAREKNRWDDDVVFKNCRFVNDTLRSEFHKKF
MEKYIK
Ligand information
>9fmd Chain 6 (length=97) [
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gugcucgcuucggcagcacauauacuaaaauuggaacgauacagagaaga
uuagcauggccccugcgcaaggaugacacgcaaauucgugaagcguu
<<<<<.<<....>>>>>>>...............................
......<<...<<<.....>>>....>>...................
Receptor-Ligand Complex Structure
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PDB
9fmd
Mechanism for the initiation of spliceosome disassembly.
Resolution
3.3 Å
Binding residue
(original residue number in PDB)
T2 T3 A4 R6 T8 P11 A12 R33 D34
Binding residue
(residue number reindexed from 1)
T1 T2 A3 R5 T7 P10 A11 R32 D33
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0005515
protein binding
Biological Process
GO:0000398
mRNA splicing, via spliceosome
GO:0006397
mRNA processing
GO:0008380
RNA splicing
GO:0045292
mRNA cis splicing, via spliceosome
Cellular Component
GO:0000974
Prp19 complex
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005681
spliceosomal complex
GO:0005739
mitochondrion
GO:0016607
nuclear speck
GO:0071007
U2-type catalytic step 2 spliceosome
GO:0071013
catalytic step 2 spliceosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:9fmd
,
PDBe:9fmd
,
PDBj:9fmd
PDBsum
9fmd
PubMed
38925148
UniProt
Q9P013
|CWC15_HUMAN Spliceosome-associated protein CWC15 homolog (Gene Name=CWC15)
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