Structure of PDB 1g5b Chain C Binding Site BS03

Receptor Information
>1g5b Chain C (length=221) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRYYEKIDGSKYRNIWVVGDLHGCYTNLMNKLDTIGFDNKKDLLISVGDL
VDRGAENVECLELITFPWFRAVRGNHEQMMIDGLSERGNVNHWLLNGGGW
FFNLDYDKEILAKALAHKADELPLIIELVSKDKKYVICHADYPFDEYEFG
KPVDHQQVIWNRERISNSQNGIVKEIKGADTFIFGHTPAVKPLKFANQMY
IDTGAVFCGNLTLIQVQGAGA
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1g5b Chain C Residue 3003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1g5b Structure of the bacteriophage lambda Ser/Thr protein phosphatase with sulfate ion bound in two coordination modes.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		H22 D49 R53 N75 H76 H186
Binding residue
(residue number reindexed from 1)		H22 D49 R53 N75 H76 H186
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0017018 myosin phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0110154 RNA decapping
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1g5b, PDBe:1g5b, PDBj:1g5b
PDBsum1g5b
PubMed11112522
UniProtP03772|PP_LAMBD Serine/threonine-protein phosphatase

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