Structure of PDB 6mwn Chain H Binding Site BS02
Receptor Information
>6mwn Chain H (length=225) Species:
9606
(Homo sapiens) [
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EVQLVESGGGLVQPGGSLRLSCAASGFSLSSSSMHWVRQAPGKGLEWVAS
ISPYSGSTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARTK
YHYKNYYWWALDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKVEPK
Ligand information
>6mwn Chain B (length=92) [
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ggcaaacaucauuuggccuuaaaugggauucugugagaggggaucccucc
auugacagcuggacuguucuuuggggccuuaugugguguuug
..<<<<<<<<<<..<<<<......<<<<<<<<.......>>>>>>>>.<<
<..<<<<<.....>>>>.>..>>>>>>>....>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
6mwn
A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Resolution
2.838 Å
Binding residue
(original residue number in PDB)
E4 L173 S175 S201 T205 Q206
Binding residue
(residue number reindexed from 1)
E1 L170 S172 S198 T202 Q203
Binding affinity
PDBbind-CN
: Kd=44nM
External links
PDB
RCSB:6mwn
,
PDBe:6mwn
,
PDBj:6mwn
PDBsum
6mwn
PubMed
31399592
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