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Structure of PDB 6wat Chain FC Binding Site BS02

Receptor Information

>6wat Chain FC (length=59) Species: 9606 (Homo sapiens)

RPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKD
ISPAALPGE

Ligand information

>6wat Chain L (length=9) Species: 9606 (Homo sapiens)

ATKVARKSA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6wat Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
• Resolution: 1.8 Å
• Binding residue (original residue number in PDB): W41 L45 L46 Y47 F65 E66 D67 F71
• Binding residue (residue number reindexed from 1): W14 L18 L19 Y20 F38 E39 D40 F44

External links

• PDB: RCSB:6wat, PDBe:6wat, PDBj:6wat
• PDBsum: 6wat
• PubMed: 32869745
• UniProt: O43189|PHF1_HUMAN PHD finger protein 1 (Gene Name=PHF1)

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