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Structure of PDB 7b1h Chain E Binding Site BS02

Receptor Information
>7b1h Chain E (length=122) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTE
NQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRR
QDSIPAFLSSLTLELFSRQTVA
Ligand information
>7b1h Chain H (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PTVHTKEALGFIMNMFQAPTS
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7b1h Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
S610 L613 K614 R617 L618 V621 F622 F629
Binding residue
(residue number reindexed from 1)
S14 L17 K18 R21 L22 V25 F26 F33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007094 mitotic spindle assembly checkpoint signaling

View graph for
Biological Process
External links
PDB RCSB:7b1h, PDBe:7b1h, PDBj:7b1h
PDBsum7b1h
PubMed34013668
UniProtQ9Y6D9|MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (Gene Name=MAD1L1)

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