BioLiP

Structure of PDB 7egr Chain D Binding Site BS02

Receptor Information

>7egr Chain D (length=206) Species: 6500 (Aplysia californica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVD
LVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQV
LSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSG
FEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLV
VKFRER

Ligand information

>7egr Chain M (length=13) Species: 101314 (Conus regius) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GCCSDPRCRYRCR

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7egr Co-crystal structure of Ac-AChBPP in complex with RgIA
Resolution	2.503 Å
Binding residue (original residue number in PDB)	Y110 W164 V165 Y166 Y205 C207 C208 E210 Y212 I213
Binding residue (residue number reindexed from 1)	Y92 W146 V147 Y148 Y187 C189 C190 E192 Y194 I195

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004888	transmembrane signaling receptor activity
GO:0005216	monoatomic ion channel activity
GO:0005230	extracellular ligand-gated monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0034220	monoatomic ion transmembrane transport

	Cellular Component
GO:0016020	membrane

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PDB	RCSB:7egr, PDBe:7egr, PDBj:7egr
PDBsum	7egr
PubMed
UniProt	Q8WSF8