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Structure of PDB 4zcf Chain C Binding Site BS02

Receptor Information
>4zcf Chain C (length=627) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLEKNLPHQKAGVDAVMNVFVSATPHLTDNVAVRLLANPELKLSEQQYYN
NIKNVQAFNGIAHSKDNHNAKSNIIDVSMETGTGKTYTYIKTIFDLNKSF
GINKFIIIVPTLSIKAGTVNFLKSDALKEHFRDDYKRELRTYVVESQKMP
QAIHDFVEASNFKKYIHVLVINSGMINSKSLTDTYDTGLLDNQFNTPVDA
LRAVKPFIIIDEPHRFPTGKKTWENIEKFNAQYIIRYGATFSEGYKNLVY
RLTAVDAFNDDLVKGIDAYIEDNANLKFVKDGKEATFFKLAKSLSKTHSA
IHDLTLDALNTAVLSNGIELKIGSSINPYSYDQTLADNMMRKAVKEHFKL
EKELLTQPRIKPLTLFFIDDLKTKFEEYVLAEANELLYKNYLEKTVTNIS
SVHGGYIEQEINEILHDKELLLSLDNPRRFIFSKWTLREGWDNPNVFQIC
KLRSSKLQEVGRGLRLPVNEYMCRVKNFTLKYYVDFTEKDFVDSLVKEVN
ESSPSKFTQELKEQIDNFKDSDAYSRLKSELKELWDLINQKAVIEYKINS
ESEFLSIFKSFMLEETERSYREFLDNLSQTIFVKHGTLHKVFCDIKDTIL
NIQTIRKIKSGFSKYLLNNSFSLGYNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zcf Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		T116 L117 S151 N187 G189 M190 S193 K194 G352 I353 E354
Binding residue
(residue number reindexed from 1)		T111 L112 S146 N172 G174 M175 S178 K179 G317 I318 E319
Enzymatic activity
Enzyme Commision number 3.1.21.5: type III site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0004519 endonuclease activity
GO:0005524 ATP binding
GO:0015668 type III site-specific deoxyribonuclease activity
GO:0016787 hydrolase activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:4zcf, PDBe:4zcf, PDBj:4zcf
PDBsum4zcf
PubMed26067164
UniProtQ5ZND2|T3RE_ECOLX Type III restriction-modification enzyme EcoP15I Res subunit (Gene Name=res)

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