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Structure of PDB 4j2x Chain C Binding Site BS02

Receptor Information
>4j2x Chain C (length=421) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLM
GSGWKKKKEQMETDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAK
TLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKN
ADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLD
DDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDA
DDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGA
SWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQ
NFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPV
TLVRNDGVIYSTSLTFTYTPE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4j2x Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		G234 N235 F236 E259 E260 F261 T262 V263 D265 V277 G282 M283 A284 P286 I332 Q333
Binding residue
(residue number reindexed from 1)		G182 N183 F184 E207 E208 F209 T210 V211 D213 V225 G230 M231 A232 P234 I280 Q281
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4j2x, PDBe:4j2x, PDBj:4j2x
PDBsum4j2x
PubMed24290140
UniProtP31266|SUH_MOUSE Recombining binding protein suppressor of hairless (Gene Name=Rbpj)

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