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Structure of PDB 1h88 Chain C Binding Site BS02

Receptor Information

>1h88 Chain C (length=152) Species: 10090 (Mus musculus)

GKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNP
ELIKGPWTKEEDQRVIKLVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHL
NPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNST
MR

Ligand information

>1h88 Chain E (length=26)

ccagtccgttaaggattgcgccacat

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1h88 Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): K113 R114 W115 R131 N164 R165 W166 A167 K182
• Binding residue (residue number reindexed from 1): K75 R76 W77 R93 N126 R127 W128 A129 K144
• Binding affinity: PDBbind-CN: Kd=35.3nM

External links

• PDB: RCSB:1h88, PDBe:1h88, PDBj:1h88
• PDBsum: 1h88
• PubMed: 11792321
• UniProt: P06876|MYB_MOUSE Transcriptional activator Myb (Gene Name=Myb)

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