Structure of PDB 8q43 Chain B Binding Site BS02

Receptor Information
>8q43 Chain B (length=428) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDY
AKKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTG
GTKTMVVHIYNFLKEKFKFEGSYLDARDYKLVYDYSEEAISLKDTIKIDI
NTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGEDFV
KWLEDPFRKIFKGENKLLEKTAKFKKHIEKLDSSPIVKFNEKTPQFIWDI
LNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWFEWYVYS
QIKSELLDRKLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLIGISLTT
SSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQKDLAYET
GSTQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q43 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution2.28 Å
Binding residue
(original residue number in PDB)		T12 P16 S36 T47 T99 G101 T102 K103 Y128 A131 R132 E384 T409 G410
Binding residue
(residue number reindexed from 1)		T12 P16 S36 T47 T99 G101 T102 K103 Y123 A126 R127 E375 T400 G401
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q43, PDBe:8q43, PDBj:8q43
PDBsum8q43
PubMed38033326
UniProtE8URK0

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