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BioLiP

Structure of PDB 6q1u Chain B Binding Site BS02

Receptor Information
>6q1u Chain B (length=244) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FDCGKPQVEPKKCPVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEW
VLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDI
ALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLL
KEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC
FEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6q1u Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.
Resolution2.3467 Å
Binding residue
(original residue number in PDB)		F587 H603 R719 S736 C737 Q738 G739 S741 S760 W761 G762 L763
Binding residue
(residue number reindexed from 1)		F40 H56 R172 S189 C190 Q191 G192 S194 S213 W214 G215 L216
Enzymatic activity
Catalytic site (original residue number in PDB) H603 D646 Q738 G739 D740 S741
Catalytic site (residue number reindexed from 1) H56 D99 Q191 G192 D193 S194
Enzyme Commision number 3.4.21.7: plasmin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6q1u, PDBe:6q1u, PDBj:6q1u
PDBsum6q1u
PubMed32270580
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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