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Structure of PDB 4q94 Chain B Binding Site BS02

Receptor Information

>4q94 Chain B (length=129) Species: 9606 (Homo sapiens)

SSFSESALEKKLSELSNSQHSVQTLSLWLIHHRKHAGPIVSVWHRELRKA
KSNRKLTFLYLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCK
KPLERLLNIWQERSVYGGEFIQQLKLSME

Ligand information

>4q94 Chain D (length=12)

SPSYSPTSPSYS

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4q94 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.
• Resolution: 1.85 Å
• Binding residue (original residue number in PDB): N18 S19 Q20 V23 Y61 N64 D65 Q68 K71
• Binding residue (residue number reindexed from 1): N17 S18 Q19 V22 Y60 N63 D64 Q67 K70

External links

• PDB: RCSB:4q94, PDBe:4q94, PDBj:4q94
• PDBsum: 4q94
• PubMed: 24997600
• UniProt: Q9NQG5|RPR1B_HUMAN Regulation of nuclear pre-mRNA domain-containing protein 1B (Gene Name=RPRD1B)

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