BioLiP

Structure of PDB 2byp Chain B Binding Site BS02

Receptor Information

>2byp Chain B (length=213) Species: 6500 (Aplysia californica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADS
STNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSS
TRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFG
SWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPY
IDVNLVVKFRERR

Ligand information

>2byp Chain H (length=12) Species: 35631 (Conus imperialis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GCCSDPRCAWRC

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2byp Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Resolution	2.07 Å
Binding residue (original residue number in PDB)	Q57 D77 R79 V108 D164
Binding residue (residue number reindexed from 1)	Q62 D82 R84 V113 D169

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004888	transmembrane signaling receptor activity
GO:0005216	monoatomic ion channel activity
GO:0005230	extracellular ligand-gated monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0034220	monoatomic ion transmembrane transport

	Cellular Component
GO:0016020	membrane

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PDB	RCSB:2byp, PDBe:2byp, PDBj:2byp
PDBsum	2byp
PubMed	16193063
UniProt	Q8WSF8