Structure of PDB 1ofz Chain B Binding Site BS02

Receptor Information
>1ofz Chain B (length=312) Species: 5188 (Aleuria aurantia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTEFLYTSKIAAISWAATGGRQQRVYFQDLNGKIREAQRGGDNPWTGGSS
QNVIGEAKLFSPLAAVTWKSAQGIQIRVYCVNKDNILSEFVYDGSKWITG
QLGSVGVKVGSNSKLAALQWGGSESAPPNIRVYYQKSNLSGSSIHEYVWS
GKWTAGASFGSTAPGTGIGATAIGPGRLRIYYQATDNKIREHCWDSNSWY
VGGFSASASAGVSIAAISWGSTPNIRVYWQKGREELYEAAYGGSWNTPGQ
IKDASRPTPSLPDTFIAANSSGNIDISVFFQASGVSLQQWQWISGKGWSI
GAVVPTGTPAGW
Ligand information
Ligand IDFUC
InChIInChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6+/m0/s1
InChIKeySHZGCJCMOBCMKK-SXUWKVJYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)C
OpenEye OEToolkits 1.5.0CC1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.5.0C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O)O)O)O
CACTVS 3.341C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
FormulaC6 H12 O5
Namealpha-L-fucopyranose;
alpha-L-fucose;
6-deoxy-alpha-L-galactopyranose;
L-fucose;
fucose
ChEMBLCHEMBL1232862
DrugBankDB04473
ZINCZINC000001532814
PDB chain1ofz Chain B Residue 1314 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ofz Crystal Structure of Fungal Lectin: Six-Bladed {Beta}-Propeller Fold and Novel Fucose Recognition Mode for Aleuria Aurantia Lectin
Resolution1.5 Å
Binding residue
(original residue number in PDB)		R77 E89 Q101 W149 W153
Binding residue
(residue number reindexed from 1)		R77 E89 Q101 W149 W153
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042806 fucose binding
Biological Process
GO:0030582 reproductive fruiting body development
GO:0050832 defense response to fungus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1ofz, PDBe:1ofz, PDBj:1ofz
PDBsum1ofz
PubMed12732625
UniProtP18891|LECF_ALEAU Fucose-specific lectin

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