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Structure of PDB 8wr4 Chain A Binding Site BS02

Receptor Information
>8wr4 Chain A (length=1212) Species: 59732 (Chryseobacterium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIKNILGLALGTNSIGWALVKQDFENKQGEILGMGSRIIPMSQDILGDFG
KGNSVSQTAERTKYRSVRRLRERFLLRRERLHRVLYILNFLPEHYASQID
FEKRLGKFKVETEPKLVWKNTDGQFSFLFQNSFNEMLEDFKAAGQELKIP
YDWTIYHLRKKAISQKIEKEELAWILLNFNHKRGYYQLRGEDFEEEKDKT
FVRLKVDRIVDSGENVKGKILYDVYFENGWKYDKQVVKTEDWVDRTKEFI
VSESILKNGETKRTFKAVDSEKDWIAIKTKTEQEIEHSHKTVGTYIYETL
LQNPKQKIKGKLVRTIERKFYKEELRQILEKQKEFHQELQSDDLYNDCIR
ELYRNNEVHQLTLRKKDFVHLFMEDIIFYQRPLRSQKSSVSNCTLEFRKY
KGENGAEHTQYLKAIPKSNPYYQEFRLWQWIFNLNLYTKDNDENVTKVFL
NTTQDFENLFEFLNTRKEVDQKALLKHFKLNEKTHRWNFVEDKKYPCNET
KTMISSRLDKVENISDDFLTRDIEQKIWHIIYSVNDKVEYEKALKSFARK
HHLDESSFFEAFRKFPPFKSEYGSFSEKAIKKLLPLMRLGKYWNYAEIDK
YSRERIQKIITGEYDENIKDKVREKSVHLTIENDFQGLQLWLAQYIVYGR
HSEASMIGKWNSANDLEVFLKDFKQHSLRNPIVEQVITETLRVVKDIWLK
YGNGTKDFFNEIHIELGDTRYISKYISGILSNIVRVEDGSDEGVNSKNIV
PGNGKITTQLKQDWGLNDVWNDLILPRFERMNQLTNSKDFTAWNENHQKF
LPTVPIEFSKGFSKKRIDHRHHALDALVIACATTDHVNLLNNQSAKSDTK
RYDLKKKLMKFPKQFLKPWEKFTVDAKHNLESIIVSFKQNLRVINKATNY
YEKYVEKDGTKNKERVEQAGTNWAIRKPMHKDTVSGKVDLPWVKVPKGKI
LTATRKSLDSSFDLKSIGSITDTGIQKILKNYLAFKDGNPELAFSPEGID
DLNKNIEKYNDGKPHQPINKVRVFELGSKFQVGQTGNKKGKYVEAAKGTN
LFFAVYEDEKGKRSYETIPLNEVIERQKQGLTSVPLENEKGSRLLFDLSP
NDLVYVPEIDENIDSNFVFSNLNKEKISRIYKVEKTSGTECYFVRQDIAY
LIKQYDAKTKIGELESQNKLQVTMTDDRIRITDTCVKINCDRLGNINFIT
KEKIKQIFNEFR
Ligand information
>8wr4 Chain O (length=100) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaacagccgagguugugaauugcuuucaaaaauuuugaaaagcaauucac
aauaaggauuauuccguugugaaaacauucaaggcggggcaacucgccuu
...........<<<<<<<<<<<<<<<..<<<<>>>>..>>>>>>>>>>>>
>>>..<<......>>..<<<....>>>...<<<<<<<<....>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wr4 Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		S56 T58 R61 T62 Y64 R65 R68 R69 L70 R71 R73 L76 R78 R80 R83 E113 W118 F125 K148 I149 P150 Y151 D152 W153 Y156 N178 H181 K182 R183 G184 K307 I308 K309 G310 R314 N355 N356 V358 H359 T362 K366 D375 Y379 Q380 R381 L383 R384 S385 K387 R398 K399 Y400 Q410 W528 H529 Y532 S533 E539 K542 S546 E577 K578 K581 Q675 H676 R679 R692 K1118 R1122 N1125 K1126 N1129 Y1131 E1132 Y1134 K1143 R1145 Q1148 N1152 W1153 I1155 R1156 K1157 P1158 M1159 H1160 V1164 V1168 D1169 R1185 T1201 D1202 T1203 G1204 K1243 P1244 H1245 Q1246 P1247 N1249 K1250 R1252 V1262 T1265 N1267 K1268 G1270 K1271
Binding residue
(residue number reindexed from 1)		S56 T58 R61 T62 Y64 R65 R68 R69 L70 R71 R73 L76 R78 R80 R83 E113 W118 F125 K148 I149 P150 Y151 D152 W153 Y156 N178 H181 K182 R183 G184 K307 I308 K309 G310 R314 N355 N356 V358 H359 T362 K366 D375 Y379 Q380 R381 L383 R384 S385 K387 R398 K399 Y400 Q410 W528 H529 Y532 S533 E539 K542 S546 E577 K578 K581 Q675 H676 R679 R692 K888 R892 N895 K896 N899 Y901 E902 Y904 K913 R915 Q918 N922 W923 I925 R926 K927 P928 M929 H930 V934 V938 D939 R955 T971 D972 T973 G974 K1013 P1014 H1015 Q1016 P1017 N1019 K1020 R1022 V1032 T1035 N1037 K1038 G1040 K1041
External links

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417