Structure of PDB 4zcf Chain A Binding Site BS02

Receptor Information
>4zcf Chain A (length=616) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANSKQLAVLKANFPQCFDKNGAFIQEKLLEIIRASEKESYSLNWLGKSYA
RLLANLPPKTLLAEDKTHNQQEENKNSQHLLIKGDNLEVLKHMVNAYAEK
VKMIYIDPPYNTGKDGFVYNDDRFTPEQLSELAGIDLDEAKRILEFTTKG
SSSHSAWLTFIYPRLYIARELMREDGTIFISIDHNEFSQLKLVCDEIFGE
QNHVGDLVWKNATDNNPSNIAVEHEYIIVYTKNKEQLISEWKSNISDVKN
LLVNIGEEFASKYTGNELQEKYTQWFREHRSELWPLDRYKYIDKDGIYTG
SQSVHNPGKEGYRYDIIHPKTKKPCKQPLMGYRFPLDTMDRLLSEEKIIF
GDDENKIIELKVYAKDYKQKLSSVIHLDGRVATNELKELFPMTQPFNAKT
IKLVEDLISFACDGEGIVLDFFAGSGTTAHTVFNLNNKNKTSYQFITVQL
DEPTKKSDAMKHGYNTIFDLTKERLIRASKKNRDQGFKVYQLMPDFRAKD
ESELTFFDDVVLTPEQYDTLLTTWCLYDGSLLTTPIEDVDLGGYKAHLCD
GRLYLIAPNFTSEALKALLQKVDSDKDFAPNKVVFYGSNFSAKQMELNEA
LKSYANSIELDLVVRN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4zcf Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		W301 R305 Y306 S320 N323 P324 Y329 R350 F351 P352 T355
Binding residue
(residue number reindexed from 1)		W284 R288 Y289 S303 N306 P307 Y312 R333 F334 P335 T338
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4zcf, PDBe:4zcf, PDBj:4zcf
PDBsum4zcf
PubMed26067164
UniProtP12364|T3MO_ECOLX Type III restriction-modification enzyme EcoP15I Mod subunit (Gene Name=mod)

[Back to BioLiP]