Structure of PDB 1lvm Chain A Binding Site BS02

Receptor Information
>1lvm Chain A (length=229) Species: 12227 (Tobacco etch virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHHHHHHHGESLFKGPRDYNPISSTICHLTNESDGHTTSLYGIGFGPFII
TNKHLFRRNNGTLLVQSLHGVFKVKNTTTLQQHLIDGRDMIIIRMPKDFP
PFPQKLKFREPQREERICLVTTNFQTKSMSSMVSDTSCTFPSSDGIFWKH
WIQTKDGQCGSPLVSTRDGFIVGIHSASNFTNTNNYFTSVPKNFMELLTN
QEAQQWVSGWRLNADSVLWGGHKVFMDKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1lvm Structural basis for the substrate specificity of tobacco etch virus protease.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
V63 F64 K65 K67 D90
Binding residue
(residue number reindexed from 1)
V71 F72 K73 K75 D98
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.-.-
3.4.22.44: nuclear-inclusion-a endopeptidase.
3.4.22.45: helper-component proteinase.
3.6.4.-
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1lvm, PDBe:1lvm, PDBj:1lvm
PDBsum1lvm
PubMed12377789
UniProtP04517|POLG_TEV Genome polyprotein

[Back to BioLiP]