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Structure of PDB 2fg6 Chain X Binding Site BS01

Receptor Information
>2fg6 Chain X (length=322) Species: 272559 (Bacteroides fragilis NCTC 9343) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGSHMKKFTCVQDIGDLKSALAESFEIKKDRFKYVELGRNKTLLMIFFNS
SLRTRLSTQKAALNLGMNVIVLDINQGAWKLETERGVIMDGDKPEHLLEA
IPVMGCYCDIIGVRSFARFENREYDYNEVIINQFIQHSGRPVFSMEAATR
HPLQSFADLITIEEYKKTARPKVVMTWAPHPRPLPQAVPNSFAEWMNATD
YEFVITHPEGYELDPKFVGNARVEYDQMKAFEGADFIYAKNWAAYLGDNY
GQILSTDRNWTVGDRQMAVTNNAYFMHCLPVRRNMIVTDDVIESPQSIVI
PEAANREISATVVLKRLLENLP
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain2fg6 Chain X Residue 346 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2fg6 Structure and catalytic mechanism of a novel N-succinyl-L-ornithine transcarbamylase in arginine biosynthesis of Bacteroides fragilis.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S47 L48 R49 T50 R110
Binding residue
(residue number reindexed from 1)		S51 L52 R53 T54 R114
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K236
Catalytic site (residue number reindexed from 1) K240
Enzyme Commision number 2.1.3.11: N-succinylornithine carbamoyltransferase.
Gene Ontology
Molecular Function
GO:0004585 ornithine carbamoyltransferase activity
GO:0016597 amino acid binding
GO:0016740 transferase activity
GO:0016743 carboxyl- or carbamoyltransferase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0019240 citrulline biosynthetic process
GO:0042450 arginine biosynthetic process via ornithine

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Molecular Function
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Biological Process
External links

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