Structure of PDB 6zqc Chain US Binding Site BS01

Receptor Information
>6zqc Chain US (length=494) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVLLISEIKDIAKKQYNSIIKLINELVIPENVTQLEEDETEKNLRFLVMS
LFQIFRKLFSRGDLTLPSSKKSTLEKEQFVNWCRKVYEAFKTKLLAIISD
IPFETSLGLDSLDVYLQLAELESTHFNKTFRKLIIALWSSNMGEIEDVKS
SGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQDLLLKNVGK
WLALVNHDKHCSSVDADLEIFVPNPPQAIENESKFKSNFEKNWLSLLNGQ
LSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPIL
ALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSS
THLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHN
PAFISNPFQTPDQVANLKTLKENYVDPFDVHESDPELTHALDSSLWELAS
LMEHYHPNVATLAKIFAQPFKKLSYNMEDFLDWNYDSLLNAESS
Ligand information
>6zqc Chain D2 (length=446) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augcgaaagcaguugaagacaagugcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaug
.<<<....>>>...<<<<<<<<<..>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<...<<<<<..<<<<<<<<<<.<<
<<<<<<....>>>>>>>>.>>>>>>>>>>.>>>>>..>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<..<
<<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>
>.....<<<<<<...<<<<<<<<<<<<<<<<........>>>>>>>.>.>
>>>>>>>....>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zqc 90 S pre-ribosome transformation into the primordial 40 S subunit.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		K146 Q245 S251
Binding residue
(residue number reindexed from 1)		K128 Q227 S233
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0030692 Noc4p-Nop14p complex
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zqc, PDBe:6zqc, PDBj:6zqc
PDBsum6zqc
PubMed32943521
UniProtQ06512|NOC4_YEAST Nucleolar complex protein 4 (Gene Name=NOC4)

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