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Structure of PDB 4dx9 Chain U Binding Site BS01

Receptor Information

>4dx9 Chain U (length=101) Species: 9606 (Homo sapiens)

CAEFRIKYVGAIEKLGPLDLINYIDVAQQDFVPPEEEFIMGVSKYGIKHR
HALYLIIRMVCYDDKSLLALKTTYSLWVYQCNSLEQAQAICKVLSTAFDS
V

Ligand information

>4dx9 Chain V (length=10) Species: 9606 (Homo sapiens)

KSAVTTVVNP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4dx9 Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation.
• Resolution: 2.99 Å
• Binding residue (original residue number in PDB): I89 I139 R140 M141 V142 C143 Q181 C184 F191
• Binding residue (residue number reindexed from 1): I21 I57 R58 M59 V60 C61 Q88 C91 F98

External links

• PDB: RCSB:4dx9, PDBe:4dx9, PDBj:4dx9
• PDBsum: 4dx9
• PubMed: 23317506
• UniProt: O14713|ITBP1_HUMAN Integrin beta-1-binding protein 1 (Gene Name=ITGB1BP1)

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