Structure of PDB 6d83 Chain S Binding Site BS01

Receptor Information
>6d83 Chain S (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFV
DWKELKLVYKRYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCE
LDIIFNFEKAYFILDEFIIGGEIQETSKKIAVKAIEDSDMLQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6d83 HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Resolution4.27 Å
Binding residue
(original residue number in PDB)		V98 C99 E100
Binding residue
(residue number reindexed from 1)		V98 C99 E100
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0035615 clathrin adaptor activity
Biological Process
GO:0006605 protein targeting
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0060155 platelet dense granule organization
GO:1903232 melanosome assembly
Cellular Component
GO:0000139 Golgi membrane
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005905 clathrin-coated pit
GO:0030117 membrane coat
GO:0030121 AP-1 adaptor complex
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0032588 trans-Golgi network membrane
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6d83, PDBe:6d83, PDBj:6d83
PDBsum6d83
PubMed30053425
UniProtQ96PC3|AP1S3_HUMAN AP-1 complex subunit sigma-3 (Gene Name=AP1S3)

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