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BioLiP

Structure of PDB 7t2b Chain O Binding Site BS01

Receptor Information
>7t2b Chain O (length=239) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVTQTPKFRVLKTGQSMTLLCAQDMNHEYMYWYRQDPGMGLRLIHYSVGE
GTTAKGEVPDGYNVSRLKKQNFLLGLESAAPSQTSVYFCASSQGGGEQYF
GPGTRLTVTEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFFPDHV
ELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYCLSSRLRVSATFWQNPR
NHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
Ligand information
>7t2b Chain M (length=13) Species: 1313 (Streptococcus pneumoniae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TGLAWEWWRTVYE
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t2b CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		E37 Y38 Q108
Binding residue
(residue number reindexed from 1)		E28 Y29 Q93
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7t2b, PDBe:7t2b, PDBj:7t2b
PDBsum7t2b
PubMed37100059
UniProtP01850|TRBC1_HUMAN T cell receptor beta constant 1 (Gene Name=TRBC1)

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