BioLiP

Structure of PDB 7qoo Chain N Binding Site BS01

Receptor Information

>7qoo Chain N (length=320) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFD
MKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPT
YVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDS
LKAIVFKQYNQTFEDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQY
KLETKFKSGLNGSILAEREEPLRCLIKFSSPHLLEALKSLAPAGIADAPL
SPLLTCIPNKRMNYFKIRDK

Ligand information

>7qoo Chain C (length=4) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

FIID

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7qoo Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization.
Resolution	4.6 Å
Binding residue (original residue number in PDB)	F334 K335
Binding residue (residue number reindexed from 1)	F315 K316

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0007059	chromosome segregation
GO:0034080	CENP-A containing chromatin assembly

	Cellular Component
GO:0000775	chromosome, centromeric region
GO:0000776	kinetochore
GO:0000939	inner kinetochore
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome
GO:0005829	cytosol

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Biological Process

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Cellular Component

PDB	RCSB:7qoo, PDBe:7qoo, PDBj:7qoo
PDBsum	7qoo
PubMed	35525244
UniProt	Q96H22\|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)