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BioLiP

Structure of PDB 9fq0 Chain LR Binding Site BS01

Receptor Information
>9fq0 Chain LR (length=153) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLII
RKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRI
LRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKAR
KKL
Ligand information
>9fq0 Chain 1 (length=298) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaguccuucugaucgaggcccagcccguggacggugugaggccgguagu
ugaaaagaacuuugaagagagaguucaagagggcgccgcccggaggauuc
aacccggcggcggguccggccgugucggcggcccggcggaucuuucccgc
gcgggggaccgucccccgaccggcgaccggccgccgccgggcgcauuucc
accgcggcgguucaaacgagaacuuugaaucggguucagauccccgaauc
uuggaaagcgucgcgguuccggcggcguaagggcugggcagccgacuu
<....<<<<......>>>>.....((......<<<.....))>>>...>.
.........<<<<....>>>>...............<<<<<<<.<<<...
..<<<<<<<<<<<..<<<<<<<.......<.....<<<<.<<<..<<...
...>>>>>>>>>.>......>>>>...>>>>>>>>>>>>>>......>>>
.>>>.>>>>.<<<<<<.......>>>>>><<<<<........>>>>>...
.......<<<<<<<.......>>>>>>><<<<<<<<..>>>>>..>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9fq0 Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome
Resolution4.67 Å
Binding residue
(original residue number in PDB)		R5 K8 R9 W23 L24 P26 R38 Q39 Q40 R42 K43 R70 R71 M76 N134 K135 R136
Binding residue
(residue number reindexed from 1)		R4 K7 R8 W22 L23 P25 R37 Q38 Q39 R41 K42 R69 R70 M75 N133 K134 R135
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9fq0, PDBe:9fq0, PDBj:9fq0
PDBsum9fq0
PubMed
UniProtP84098|RL19_HUMAN Large ribosomal subunit protein eL19 (Gene Name=RPL19)

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