Structure of PDB 1dva Chain I Binding Site BS01

Receptor Information
>1dva Chain I (length=254) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWR
NLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPV
VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNV
PRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHY
RGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLR
APFP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1dva Peptide exosite inhibitors of factor VIIa as anticoagulants.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		G38 V67 E70 L73 S74 H76 E80 S82 L144 L145 D146 L153
Binding residue
(residue number reindexed from 1)		G22 V55 E58 L61 S62 H64 E68 S70 L135 L136 D137 L143
Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1dva, PDBe:1dva, PDBj:1dva
PDBsum1dva
PubMed10761907
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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