Structure of PDB 6mwn Chain H Binding Site BS01

Receptor Information
>6mwn Chain H (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVQLVESGGGLVQPGGSLRLSCAASGFSLSSSSMHWVRQAPGKGLEWVAS
ISPYSGSTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARTK
YHYKNYYWWALDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKVEPK
Ligand information
>6mwn Chain A (length=92) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcaaacaucauuuggccuuaaaugggauucugugagaggggaucccucc
auugacagcuggacuguucuuuggggccuuaugugguguuug
..<<<<<<<<<<..<<<<......<<<<<<<<.......>>>>>>>>.<<
<..<<<<.......>>.>>..>>>>>>>....>>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6mwn A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Resolution2.838 Å
Binding residue
(original residue number in PDB)		S33 S55 Y57 S58 Y104 H105 Y106 K107 N108 Y109 Y110 W111 W112
Binding residue
(residue number reindexed from 1)		S30 S52 Y54 S55 Y101 H102 Y103 K104 N105 Y106 Y107 W108 W109
Binding affinityPDBbind-CN: Kd=44nM
External links