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Structure of PDB 6kva Chain H Binding Site BS01

Receptor Information

>6kva Chain H (length=213) Species: 9606 (Homo sapiens)

QVQLVQSGAEVKKPGSSVKVSCKASGGTLSSYAISWVRQAPGQGPEWMGW
INPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRPDDTAVYYCASGY
CSRTRCYDYWGQGTLVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNH
KPSNTKVDKKVEP

Ligand information

>6kva Chain B (length=6) Species: 9606 (Homo sapiens)

FEDFWK

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6kva Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
• Resolution: 2.2 Å
• Binding residue (original residue number in PDB): Y33 A34 S36 W51 A98 G100 Y101 C102 S103
• Binding residue (residue number reindexed from 1): Y32 A33 S35 W50 A97 G99 Y100 C101 S102

External links

• PDB: RCSB:6kva, PDBe:6kva, PDBj:6kva
• PDBsum: 6kva
• PubMed: 33953162

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