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Structure of PDB 4xgz Chain H Binding Site BS01

Receptor Information

>4xgz Chain H (length=219) Species: 9606 (Homo sapiens)

SEVQLVESGGGLVQPGGSLRLSCAASGFNVSYSSIHWVRQAPGKGLEWVA
SIYSYYGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARG
YYGAAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTGGTAALGCLVKDY
FPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI
CNVNHKPSNTKVDKKVEPK

Ligand information

>4xgz Chain h (length=12) Species: 9606 (Homo sapiens)

NLSELDRLLLEL

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4xgz Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
• Resolution: 2.5 Å
• Binding residue (original residue number in PDB): S33 Y52 Y53 Y54 Y56 Y58 Y96 Y97 A99
• Binding residue (residue number reindexed from 1): S34 Y53 Y55 Y56 Y58 Y60 Y101 Y102 A104

External links

• PDB: RCSB:4xgz, PDBe:4xgz, PDBj:4xgz
• PDBsum: 4xgz
• PubMed: 26087144

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