Structure of PDB 4hix Chain H Binding Site BS01
Receptor Information
>4hix Chain H (length=219) Species:
9606
(Homo sapiens) [
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VQLLESGGGLVQPGGSLRLSCAASGFTFSNYGMSWVRQAPGKGLEWVASI
RSGGGRTYYSDNVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCVRYDH
YSGSSDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDY
FPQPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI
CNVNHKPSNTKVDKKVEPK
Ligand information
>4hix Chain A (length=6) Species:
9606
(Homo sapiens) [
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DAEFRH
Receptor-Ligand Complex Structure
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PDB
4hix
Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Resolution
2.204 Å
Binding residue
(original residue number in PDB)
G33 S50 R52 Y58 Y95 S100B
Binding residue
(residue number reindexed from 1)
G32 S49 R51 Y58 Y98 S105
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4hix
,
PDBe:4hix
,
PDBj:4hix
PDBsum
4hix
PubMed
23416764
UniProt
P01857
|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)
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