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Structure of PDB 6vme Chain G Binding Site BS01

Receptor Information

>6vme Chain G (length=75) Species: 9606 (Homo sapiens)

IDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHV
RLLSRKQFQLRALMQKARKTAGLSD

Ligand information

>6vme Chain Q (length=18) Species: 9606 (Homo sapiens)

ASSLYGISAMDGVPFTLH

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6vme A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.
• Resolution: 2.19 Å
• Binding residue (original residue number in PDB): V317 I318 I319 P320 T321 Y325 Y332 E335 R374 R381 D388
• Binding residue (residue number reindexed from 1): V4 I5 I6 P7 T8 Y12 Y19 E22 R61 R68 D75

External links

• PDB: RCSB:6vme, PDBe:6vme, PDBj:6vme
• PDBsum: 6vme
• PubMed: 32424346
• UniProt: Q99816|TS101_HUMAN Tumor susceptibility gene 101 protein (Gene Name=TSG101)

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