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BioLiP

Structure of PDB 6r25 Chain G Binding Site BS01

Receptor Information
>6r25 Chain G (length=113) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEY
LTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGV
LPNIQSVLLPKKT
Ligand information
>6r25 Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctcgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6r25 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Resolution4.61 Å
Binding residue
(original residue number in PDB)		R29 R42 V43 G44 A45 K75 T76 R77 K119
Binding residue
(residue number reindexed from 1)		R22 R35 V36 G37 A38 K68 T69 R70 K112
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6r25, PDBe:6r25, PDBj:6r25
PDBsum6r25
PubMed30970244
UniProtP06897|H2A1_XENLA Histone H2A type 1

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