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Structure of PDB 5zop Chain G Binding Site BS01

Receptor Information
>5zop Chain G (length=383) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECI
RGRKATLEELQTVHSEAHTLLYGTNPSVFVRLPCGGVGVDSDTIWNEVHS
AGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNS
VAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDD
GNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMP
IASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGR
IVLALEGGYDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSM
EKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCEN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zop Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4.
Resolution2.698 Å
Binding residue
(original residue number in PDB)		D759 F812 G868 N869 F870 F871 P872 P942
Binding residue
(residue number reindexed from 1)		D92 F145 G201 N202 F203 F204 P205 P275
Enzymatic activity
Enzyme Commision number 3.5.1.98: histone deacetylase.
External links
PDB RCSB:5zop, PDBe:5zop, PDBj:5zop
PDBsum5zop
PubMed30321390
UniProtP56524|HDAC4_HUMAN Histone deacetylase 4 (Gene Name=HDAC4)

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