Structure of PDB 7pb2 Chain F Binding Site BS01
Receptor Information
>7pb2 Chain F (length=274) Species:
9606
(Homo sapiens) [
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SHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPW
IEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYGC
DVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH
AAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>7pb2 Chain H (length=10) Species:
9606
(Homo sapiens) [
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VVVGADGVGK
Receptor-Ligand Complex Structure
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PDB
7pb2
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Resolution
3.41 Å
Binding residue
(original residue number in PDB)
Y7 Y9 E63 N66 A69 Q70 D77 T80 Y84 Y99 R114 D116 T143 W147 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 Y8 E62 N65 A68 Q69 D76 T79 Y83 Y98 R113 D115 T142 W146 Q154 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7pb2
,
PDBe:7pb2
,
PDBj:7pb2
PDBsum
7pb2
PubMed
UniProt
A0A583ZB34
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