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Structure of PDB 5c08 Chain F Binding Site BS01

Receptor Information
>5c08 Chain F (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5c08 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution2.332 Å
Binding residue
(original residue number in PDB)		Y7 M45 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 M45 E63 K66 V67 H70 T73 D77 Y84 R97 Y99 Y116 T143 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5c08, PDBe:5c08, PDBj:5c08
PDBsum5c08
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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