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BioLiP

Structure of PDB 1aou Chain F Binding Site BS01

Receptor Information
>1aou Chain F (length=106) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW
DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLSSRL
VVPSHK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1aou The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.
ResolutionN/A
Binding residue
(original residue number in PDB)		R14 R34 S36 K59 H60 Y61 K62 T74 R76 G95 L96
Binding residue
(residue number reindexed from 1)		R14 R34 S36 K59 H60 Y61 K62 T74 R76 G95 L96
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:1aou, PDBe:1aou, PDBj:1aou
PDBsum1aou
PubMed9351806
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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