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Structure of PDB 7b1h Chain E Binding Site BS01

Receptor Information

>7b1h Chain E (length=122) Species: 9606 (Homo sapiens)

SSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTE
NQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRR
QDSIPAFLSSLTLELFSRQTVA

Ligand information

>7b1h Chain G (length=18) Species: 9606 (Homo sapiens)

PTVHTKEALGFIMNMFQA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7b1h Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): K619 F622 I626 R630 Q640 I643
• Binding residue (residue number reindexed from 1): K23 F26 I30 R34 Q44 I47

Gene Ontology

Biological Process

• GO:0007094 mitotic spindle assembly checkpoint signaling

External links

• PDB: RCSB:7b1h, PDBe:7b1h, PDBj:7b1h
• PDBsum: 7b1h
• PubMed: 34013668
• UniProt: Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (Gene Name=MAD1L1)

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