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BioLiP

Structure of PDB 6gys Chain E Binding Site BS01

Receptor Information
>6gys Chain E (length=506) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDRFQELVDSLKPRTAHQYKTYYTKYIQWCQLNQIIPTNSVPYKDLPISA
ELIHWFLLDTLITDDKPGEKREETEDLDEEEENSFKIATLKKIIGSLNFL
SKLCKVHENPNANIDTKYLESVTKLHTHWIDSQKAITTNETNNTNTQVLC
PPLLKVSLNLWNPETNHLSEKFFKTCSEKLRFLVDFQLRSYLNLSFEERS
KIRFGSLKLGKRDRDAIIYHKVTHSAEKKDTPGHHQLLALLPQDCPFICP
QTTLAAYLYLRFYGIPSVSKGDGFPNLNADENGSLLQDIPILRGKSLTTY
PREETFSNYYTTVFRYCHLPYKRREYFNKCNLVYPTWDEDTFRTFFNEEN
HGNWLEQPEAFAFPDKIPFDFKKIMNFKSPYTSYSTNAKKDPFPPPKDLL
VQIFPEIDEYKRHDYEGLSQNSRDFLDLMEVLRERFLSNLPWIYKFFPNH
DIFQDPIFGNSDFQSYFNDKTIHSKGSPILSFDILPGFNKIYKNKTNFYS
LLIERP
Ligand information
>6gys Chain F (length=52) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttaaaatattagtgtatttgatttccgaaagttaaaaaagaaatagtaag
aa
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gys Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		S339 T343 R355 R356
Binding residue
(residue number reindexed from 1)		S307 T311 R323 R324
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008301 DNA binding, bending
GO:0019237 centromeric DNA binding
Biological Process
GO:0000022 mitotic spindle elongation
GO:0000921 septin ring assembly
GO:0007059 chromosome segregation
GO:0051382 kinetochore assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005816 spindle pole body
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0031518 CBF3 complex
GO:0051233 spindle midzone

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gys, PDBe:6gys, PDBj:6gys
PDBsum6gys
PubMed30478265
UniProtP32504|CBF3A_YEAST Centromere DNA-binding protein complex CBF3 subunit A (Gene Name=CBF2)

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