Structure of PDB 5tx1 Chain E Binding Site BS01

Receptor Information
>5tx1 Chain E (length=947) Species: 46928 (Human adenovirus 26) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHD
VTTDRSQRLTLRFVPVDREATTYLYKARFTLAVGDNRVLDMASTYFDIRG
VLDRGPSFKPYSGTAYNSLAPKGAPNPSQWETKEKQGTTGGVQQEKDVTK
TFGVAATGGINITNQGLLLGTDETAENGKKDIYADKTFQPEPQVGEENWQ
ENEAFYGGRALKKDTKMKPCYGSFARPTNEKGGQAKFKPVNEGEQPKDLD
IDFAYFDVPGGSPPAGGSGEEYKADIILYTENVNLETPDTHVVYKPGTSD
NSSEINLVQQSMPNRPNYIGFRDNFVGLMYYNSTGNMGVLAGQASQLNAV
VDLQDRNTELSYQLLLDSLGDRTRYFSMWNSAVDSYDPDVRIIENHGVED
ELPNYCFPLNGTGTNSTYQGVKITNGNDGAEESEWEKDDAISRQNQICKG
NVYAMEINLQANLWKSFLYSNVALYLPDSYKYTPANVKLPANTNTYEYMN
GRVVAPSLVDAYINIGARWSLDPMDNVNPFNHPRNAGLRYRSMLLGNGRY
VPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMILQSSLGNDLRVDG
ASVRFDSVNLYATFFPMAHNTASTLEAMLRNDTHDQSFNDYLSAANMLYP
IPAKATNVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGSI
PYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYN
VAQCNMTKDWFLVQMLSHYNIGYQGFHVPEGYKDRMYSFFRNFQPMSRQV
VDEINYKDYKAVTLPFQHNNSGFTGYLAPTMRQGQPYPANFPYPLIGQTA
VPSVTQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTF
EVDPMDEPTLLYLLFEVFDVVRVHQPHRGVIEAVYLRTPFSAGNATT
Ligand information
>5tx1 Chain 3 (length=26) Species: 46928 (Human adenovirus 26) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DINFASLAPRHGTRPFMGTWNEIGTS
Receptor-Ligand Complex Structure
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PDB5tx1 Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		G17 Q18 D19 E22 P48 T49 V50 P52 T53 V56 Y646 L647 S648 R676 R872
Binding residue
(residue number reindexed from 1)		G12 Q13 D14 E17 P43 T44 V45 P47 T48 V51 Y641 L642 S643 R671 R867
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tx1, PDBe:5tx1, PDBj:5tx1
PDBsum5tx1
PubMed28508067
UniProtQ3S8B3

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