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BioLiP

Structure of PDB 4jzo Chain E Binding Site BS01

Receptor Information
>4jzo Chain E (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYVLTQPPSVSVSPGQTARITCSGDKLGDKYASWYQQKPGQSPVLVIYQD
NKRPSEIPARFSGSNSGNTATLTISGAQAMDEADYYCQAWDSNTGVFGTG
TKLTVLRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVD
NALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGL
SSPVTKSFNRG
Ligand information
>4jzo Chain I (length=11) Species: 11108 (Hepatitis C virus (isolate H)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GWLAGLFYQHK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4jzo Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Resolution2.22 Å
Binding residue
(original residue number in PDB)		G28 D29 K30 Y31 Q49 D50 W90 N93
Binding residue
(residue number reindexed from 1)		G28 D29 K30 Y31 Q49 D50 W90 N93
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