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BioLiP

Structure of PDB 4z7q Chain D Binding Site BS01

Receptor Information
>4z7q Chain D (length=471) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCA
PESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNF
SIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLR
IGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQV
TRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTT
DAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLS
QKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGK
IRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIE
AKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNN
GNGTFECGVCRCGPGWLGSQC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4z7q beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		S121 Y122 S123 N215 A218 E220
Binding residue
(residue number reindexed from 1)		S121 Y122 S123 N215 A218 E220
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4z7q, PDBe:4z7q, PDBj:4z7q
PDBsum4z7q
PubMed26631735
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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