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Structure of PDB 1j73 Chain D Binding Site BS01

Receptor Information
>1j73 Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1j73 Chain C (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCASICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1j73 Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
C7 L11 L15 V18 C19 R22 F25 Y26
Binding residue
(residue number reindexed from 1)
C7 L11 L15 V18 C19 R22 F25 Y26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1j73, PDBe:1j73, PDBj:1j73
PDBsum1j73
PubMed11779231
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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