Structure of PDB 1gy3 Chain D Binding Site BS01

Receptor Information
>1gy3 Chain D (length=258) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
Ligand information
Receptor-Ligand Complex Structure
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PDB1gy3 Structural Studies on Phospho-Cdk2/Cyclin a Bound to Nitrate, a Transition State Analogue: Implications for the Protein Kinase Mechanism
Resolution2.7 Å
Binding residue
(original residue number in PDB)
E269 I270
Binding residue
(residue number reindexed from 1)
E95 I96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function

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Biological Process
External links
PDB RCSB:1gy3, PDBe:1gy3, PDBj:1gy3
PDBsum1gy3
PubMed12044161
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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