Structure of PDB 8vat Chain C Binding Site BS01

Receptor Information
>8vat Chain C (length=370) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPHMSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTR
GVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAAS
RTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPP
EHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIA
HEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAMLGTLDDD
QALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQL
SPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELPYAPDRRM
GVEMTLLRALAFHPRMPLPE
Ligand information
Receptor-Ligand Complex Structure
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PDB8vat Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T99 K100 V101 R105 S132 H134
Binding residue
(residue number reindexed from 1)		T102 K103 V104 R108 S135 H137
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8vat, PDBe:8vat, PDBj:8vat
PDBsum8vat
PubMed38490435
UniProtP06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)

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